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By James Van Straten|Edited by Stephen Alpher
May 23, 2025, 1:04 p.m.

- Semler Scientific (SMLR) acquired 455 BTC for $50M using proceeds from its ATM equity program, increasing total holdings to 4,264 bitcoin.
- The company said its so-called BTC Yield rose to 25.8% YTD.
Medical equipment company Semler Scientific (SMLR) announced its third-largest bitcoin
purchase since adopting a bitcoin standard roughly one year ago.
The company in the ten days ending May 22 acquired 455 BTC for $50 million, averaging $109,801 per bitcoin. This acquisition, funded through its at-the-market (ATM) equity offering program, brings Semler’s total holdings to 4,264 BTC, purchased for $390 million and currently valued at more than $450 million.
STORY CONTINUES BELOW
To date, the company has issued 3,003,488 shares under its April 15 $500 million ATM program, raising $114.8 million.
Now roundly used as a key performance indicator by most companies adding bitcoin to their balance sheet, Semler’s BTC Yield, has risen to 25.8% in 2025. BTC Yield measures the year-to-date percentage change in the ratio of total bitcoin holdings to assumed diluted shares outstanding.
SMLR shares are lower by 5.3% in premarket trading alongside a sizable decline in the price of bitcoin Friday morning to $108,300.
James Van Straten is a Senior Analyst at CoinDesk, specializing in Bitcoin and its interplay with the macroeconomic environment. Previously, James worked as a Research Analyst at Saidler & Co., a Swiss hedge fund, where he developed expertise in on-chain analytics. His work focuses on monitoring flows to analyze Bitcoin’s role within the broader financial system.
In addition to his professional endeavors, James serves as an advisor to Coinsilium, a UK publicly traded company, where he provides guidance on their Bitcoin treasury strategy. He also holds investments in Bitcoin and Strategy (MSTR).