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By Sam Reynolds, AI Boost|Edited by Parikshit Mishra
Jul 16, 2025, 6:22 a.m.
- Mary-Catherine Lader has stepped down as President and COO of Uniswap Labs after four years, leaving a legacy of significant expansion and innovation.
- During her tenure, Uniswap Labs launched a mobile wallet and expanded its protocol across multiple blockchains, becoming a key infrastructure provider.
- Lader’s departure coincides with a stabilized regulatory environment for Uniswap, following settlements with the SEC and CFTC over past compliance issues.
Mary-Catherine Lader, President and COO of Uniswap Labs, has stepped down after four years leading the development company behind one of the most prominent decentralized exchanges (DEX).
STORY CONTINUES BELOW
A former BlackRock executive, Lader joined Uniswap in 2021 to help bridge traditional finance and decentralized protocols.
During her tenure, Uniswap Labs expanded the protocol’s reach across multiple blockchains, launched its own mobile wallet, and matured into an infrastructure provider relied on by institutions, developers, and retail users alike. A successor has not been named.
Her exit also comes at a time when Uniswap’s regulatory standing has stabilized after facing multiple challenges over the past year.
In April 2024, the company received a Wells notice from the U.S. Securities and Exchange Commission (SEC), signaling potential enforcement action over alleged unregistered broker and exchange activity.
Later, in September 2024, Uniswap Labs settled with the CFTC, agreeing to pay a $175,000 fine for illegally offering leveraged digital asset derivatives through its interface, specifically, tokenized products that the agency deemed margined commodity contracts.
Since then, the broader U.S. policy environment has shifted. Under President Donald Trump, the White House has thrown its support behind crypto via the GENIUS Act, a proposed national bitcoin reserve, and calls for “clear and simple” regulatory frameworks.
Trump has described himself as the “crypto president,” and Congressional momentum is building around market structure legislation. Lader departs with Uniswap standing strong, anchored by over $5.3 billion in total value locked, according to DeFi Llama.
Disclaimer: Parts of this article were generated with the assistance from AI tools and reviewed by our editorial team to ensure accuracy and adherence to our standards. For more information, see CoinDesk’s full AI Policy.
Sam Reynolds is a senior reporter based in Asia. Sam was part of the CoinDesk team that won the 2023 Gerald Loeb award in the breaking news category for coverage of FTX’s collapse. Prior to CoinDesk, he was a reporter with Blockworks and a semiconductor analyst with IDC.
“AI Boost” indicates a generative text tool, typically an AI chatbot, contributed to the article. In each and every case, the article was edited, fact-checked and published by a human. Read more about CoinDesk’s AI Policy.
